Application of the Bicyclo[1.1.1]pentane Motif as a Nonclassical Phenyl Ring Bioisostere in the Design of a Potent and Orally Active γ-Secretase Inhibitor

Publication

Citation
Stepan A., Subramanyam C., Efremov I., Dutra J., O’Sullivan T., DiRico K., McDonald W., Won A., Dorff P., Nolan C., Becker S., Pustilnik L., Riddell D., Kauffman G., Kormos B., Zhang L., Lu Y., Capetta S., Green M., Karki K., Sibley E., Atchison K., Hallgren A., Oborski C., Robshaw A., Sneed B., O’Donnell C.: Application of the Bicyclo[1.1.1]pentane Motif as a Nonclassical Phenyl Ring Bioisostere in the Design of a Potent and Orally Active γ-Secretase Inhibitor. Journal of Medicinal Chemistry, Volume 55 (7), 2012
Authors
Antonia F. Stepan, Chakrapani Subramanyam, Ivan V. Efremov, Jason K. Dutra, Theresa J. O’Sullivan, Kenneth J. DiRico, W. Scott McDonald, Annie Won, Peter H. Dorff, Charles E. Nolan, Stacey L. Becker, Leslie R. Pustilnik, David R. Riddell, Gregory W. Kauffman, Bethany L. Kormos, Liming Zhang, Yasong Lu, Steven H. Capetta, Michael E. Green, Kapil Karki, Evelyn Sibley, Kevin P. Atchison, Andrew J. Hallgren, Christine E. Oborski, Ashley E. Robshaw, Blossom Sneed, Christopher J. O’Donnell
Journal
Journal of Medicinal Chemistry
Year
2012
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Palacky University Olomouc

Palacky University Olomouc

Faculty of Science

Department of Physical Chemistry

tř. 17. listopadu 1192/12

771 46 Olomouc

Czech Republic

How to cite?

Juračka J., Šrejber M., Melíková M., Bazgier V., Berka K.: MolMeDB: Molecules on Membranes Database. Database, Volume 2019, 2019, baz078, https://doi.org/10.1093/database/baz078

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