Design of Pyridopyrazine-1,6-dione γ-Secretase Modulators that Align Potency, MDR Efflux Ratio, and Metabolic Stability

Publication

Citation
Pettersson M., Johnson D., Humphrey J., Butler T., am Ende C., Fish B., Green M., Kauffman G., Mullins P., O’Donnell C., Stepan A., Stiff C., Subramanyam C., Tran T., Vetelino B., Yang E., Xie L., Bales K., Pustilnik L., Steyn S., Wood K., Verhoest P.: Design of Pyridopyrazine-1,6-dione γ-Secretase Modulators that Align Potency, MDR Efflux Ratio, and Metabolic Stability. ACS Medicinal Chemistry Letters, Volume 6 (5), 2015
Authors
Martin Pettersson, Douglas S. Johnson, John M. Humphrey, Todd W. Butler, Christopher W. am Ende, Benjamin A. Fish, Michael E. Green, Gregory W. Kauffman, Patrick B. Mullins, Christopher J. O’Donnell, Antonia F. Stepan, Cory M. Stiff, Chakrapani Subramanyam, Tuan P. Tran, Beth Cooper Vetelino, Eddie Yang, Longfei Xie, Kelly R. Bales, Leslie R. Pustilnik, Stefanus J. Steyn, Kathleen M. Wood, Patrick R. Verhoest
Journal
ACS Medicinal Chemistry Letters
Year
2015
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Palacky University Olomouc

Palacky University Olomouc

Faculty of Science

Department of Physical Chemistry

tř. 17. listopadu 1192/12

771 46 Olomouc

Czech Republic

How to cite?

Juračka J., Šrejber M., Melíková M., Bazgier V., Berka K.: MolMeDB: Molecules on Membranes Database. Database, Volume 2019, 2019, baz078, https://doi.org/10.1093/database/baz078

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