Citation

Lorthiois E, Roache J, Barnes-Seeman D, Altmann E, Hassiepen U, Turner G, Duvadie R, Hornak V, Karki RG, Schiering N, Weihofen WA, Perruccio F, Calhoun A, Fazal T, Dedic D, Durand C, Dussauge S, Fettis K, Tritsch F, Dentel C, Druet A, Liu D, Kirman L, Lachal J, Namoto K, Bevan D, Mo R, Monnet G, Muller L, Zessis R, Huang X, Lindsley L, Currie T, Chiu YH, Fridrich C, Delgado P, Wang S, Hollis-Symynkywicz M, Berghausen J, Williams E, Liu H, Liang G, Kim H, Hoffmann P, Hein A, Ramage P, D'Arcy A, Harlfinger S, Renatus M, Ruedisser S, Feldman D, Elliott J, Sedrani R, Maibaum J, Adams CM.: Structure-Based Design and Preclinical Characterization of Selective and Orally Bioavailable Factor XIa Inhibitors: Demonstrating the Power of an Integrated S1 Protease Family Approach. J Med Chem, Volume 63 (15), 2020

Authors

Altmann E, Barnes-Seeman D, Bevan D, Calhoun A, Dedic D, Dentel C, Druet A, Durand C, Dussauge S, Duvadie R, Fazal T, Fettis K, Hassiepen U, Hornak V, Karki RG, Kirman L, Lachal J, Liu D, Lorthiois E, Namoto K, Perruccio F, Roache J, Schiering N, Tritsch F, Turner G, Weihofen WA, Adams CM., Berghausen J, Chiu YH, Currie T, D'Arcy A, Delgado P, Elliott J, Feldman D, Fridrich C, Harlfinger S, Hein A, Hoffmann P, Hollis-Symynkywicz M, Huang X, Kim H, Liang G, Lindsley L, Liu H, Maibaum J, Mo R, Monnet G, Muller L, Ramage P, Renatus M, Ruedisser S, Sedrani R, Wang S, Williams E, Zessis R

Journal

J Med Chem

Year

2020

DOI

10.1021/acs.jmedchem.0c00279

PubMed

32551603

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