Citation

Certal V, Carry JC, Halley F, Virone-Oddos A, Thompson F, Filoche-Rommé B, El-Ahmad Y, Karlsson A, Charrier V, Delorme C, Rak A, Abecassis PY, Amara C, Vincent L, Bonnevaux H, Nicolas JP, Mathieu M, Bertrand T, Marquette JP, Michot N, Benard T, Perrin MA, Lemaitre O, Guerif S, Perron S, Monget S, Gruss-Leleu F, Doerflinger G, Guizani H, Brollo M, Delbarre L, Bertin L, Richepin P, Loyau V, Garcia-Echeverria C, Lengauer C, Schio L.: Discovery and optimization of pyrimidone indoline amide PI3Kβ inhibitors for the treatment of phosphatase and tensin homologue (PTEN)-deficient cancers. J Med Chem, Volume 57 (3), 2014

Authors

Abecassis PY, Amara C, Benard T, Bertin L, Bertrand T, Bonnevaux H, Brollo M, Carry JC, Certal V, Charrier V, Delbarre L, Delorme C, Doerflinger G, El-Ahmad Y, Filoche-Rommé B, Garcia-Echeverria C, Gruss-Leleu F, Guerif S, Guizani H, Halley F, Karlsson A, Lemaitre O, Lengauer C, Loyau V, Marquette JP, Mathieu M, Michot N, Monget S, Nicolas JP, Perrin MA, Perron S, Rak A, Richepin P, Schio L., Thompson F, Vincent L, Virone-Oddos A

Journal

J Med Chem

Year

2014

DOI

10.1021/jm401642q

PubMed

24387221

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