{"data":{"id":3572,"citation":"Certal V, Carry JC, Halley F, Virone-Oddos A, Thompson F, Filoche-Romm\u00e9 B, El-Ahmad Y, Karlsson A, Charrier V, Delorme C, Rak A, Abecassis PY, Amara C, Vincent L, Bonnevaux H, Nicolas JP, Mathieu M, Bertrand T, Marquette JP, Michot N, Benard T, Perrin MA, Lemaitre O, Guerif S, Perron S, Monget S, Gruss-Leleu F, Doerflinger G, Guizani H, Brollo M, Delbarre L, Bertin L, Richepin P, Loyau V, Garcia-Echeverria C, Lengauer C, Schio L.: Discovery and optimization of pyrimidone indoline amide PI3K\u03b2 inhibitors for the treatment of phosphatase and tensin homologue (PTEN)-deficient cancers. J Med Chem, Volume 57 (3), 2014","title":"Discovery and optimization of pyrimidone indoline amide PI3K\u03b2 inhibitors for the treatment of phosphatase and tensin homologue (PTEN)-deficient cancers.","doi":"10.1021\/jm401642q","doi_url":"https:\/\/doi.org\/10.1021\/jm401642q","pmid":"24387221","pmid_url":"https:\/\/pubmed.ncbi.nlm.nih.gov\/24387221\/","year":2014,"journal":"J Med Chem","volume":"57","issue":"3","page":"903-920","authors":[{"first_name":"Abecassis PY","last_name":null,"full_name":null},{"first_name":"Amara C","last_name":null,"full_name":null},{"first_name":"Benard T","last_name":null,"full_name":null},{"first_name":"Bertin L","last_name":null,"full_name":null},{"first_name":"Bertrand T","last_name":null,"full_name":null},{"first_name":"Bonnevaux H","last_name":null,"full_name":null},{"first_name":"Brollo M","last_name":null,"full_name":null},{"first_name":"Carry JC","last_name":null,"full_name":null},{"first_name":"Certal V","last_name":null,"full_name":null},{"first_name":"Charrier V","last_name":null,"full_name":null},{"first_name":"Delbarre L","last_name":null,"full_name":null},{"first_name":"Delorme C","last_name":null,"full_name":null},{"first_name":"Doerflinger G","last_name":null,"full_name":null},{"first_name":"El-Ahmad Y","last_name":null,"full_name":null},{"first_name":"Filoche-Romm\u00e9 B","last_name":null,"full_name":null},{"first_name":"Garcia-Echeverria C","last_name":null,"full_name":null},{"first_name":"Gruss-Leleu F","last_name":null,"full_name":null},{"first_name":"Guerif S","last_name":null,"full_name":null},{"first_name":"Guizani H","last_name":null,"full_name":null},{"first_name":"Halley F","last_name":null,"full_name":null},{"first_name":"Karlsson A","last_name":null,"full_name":null},{"first_name":"Lemaitre O","last_name":null,"full_name":null},{"first_name":"Lengauer C","last_name":null,"full_name":null},{"first_name":"Loyau V","last_name":null,"full_name":null},{"first_name":"Marquette JP","last_name":null,"full_name":null},{"first_name":"Mathieu M","last_name":null,"full_name":null},{"first_name":"Michot N","last_name":null,"full_name":null},{"first_name":"Monget S","last_name":null,"full_name":null},{"first_name":"Nicolas JP","last_name":null,"full_name":null},{"first_name":"Perrin MA","last_name":null,"full_name":null},{"first_name":"Perron S","last_name":null,"full_name":null},{"first_name":"Rak A","last_name":null,"full_name":null},{"first_name":"Richepin P","last_name":null,"full_name":null},{"first_name":"Schio L.","last_name":null,"full_name":null},{"first_name":"Thompson F","last_name":null,"full_name":null},{"first_name":"Vincent L","last_name":null,"full_name":null},{"first_name":"Virone-Oddos A","last_name":null,"full_name":null}],"url":"https:\/\/molmedb.upol.cz\/api\/v1\/publications\/3572","landing_page":"https:\/\/molmedb.upol.cz\/publication\/3572","created_at":"2024-05-21T20:12:32.000000Z","updated_at":null}}