Discovery of Potent, Selective, and State-Dependent Na<sub>V</sub>1.7 Inhibitors with Robust Oral Efficacy in Pain Models: Structure-Activity Relationship and Optimization of Chroman and Indane Aryl Sulfonamides.

Publication

Citation
Ramdas V, Talwar R, Kanoje V, Loriya RM, Banerjee M, Patil P, Joshi AA, Datrange L, Das AK, Walke DS, Kalhapure V, Khan T, Gote G, Dhayagude U, Deshpande S, Shaikh J, Chaure G, Pal RR, Parkale S, Suravase S, Bhoskar S, Gupta RV, Kalia A, Yeshodharan R, Azhar M, Daler J, Mali V, Sharma G, Kishore A, Vyawahare R, Agarwal G, Pareek H, Budhe S, Nayak A, Warude D, Gupta PK, Joshi P, Joshi S, Darekar S, Pandey D, Wagh A, Nigade PB, Mehta M, Patil V, Modi D, Pawar S, Verma M, Verma M, Singh M, Das S, Gundu J, Nemmani K, Bock MG, Sharma S, Bakhle D, Kamboj RK, Palle VP.: Discovery of Potent, Selective, and State-Dependent Na<sub>V</sub>1.7 Inhibitors with Robust Oral Efficacy in Pain Models: Structure-Activity Relationship and Optimization of Chroman and Indane Aryl Sulfonamides. J Med Chem, Volume 63 (11), 2020
Authors
Banerjee M, Chaure G, Das AK, Datrange L, Deshpande S, Dhayagude U, Gote G, Joshi AA, Kalhapure V, Kanoje V, Khan T, Loriya RM, Pal RR, Parkale S, Patil P, Ramdas V, Shaikh J, Talwar R, Walke DS, Agarwal G, Azhar M, Bakhle D, Bhoskar S, Bock MG, Budhe S, Daler J, Darekar S, Das S, Gundu J, Gupta PK, Gupta RV, Joshi P, Joshi S, Kalia A, Kamboj RK, Kishore A, Mali V, Mehta M, Modi D, Nayak A, Nemmani K, Nigade PB, Palle VP., Pandey D, Pareek H, Patil V, Pawar S, Sharma G, Sharma S, Singh M, Suravase S, Verma M, Vyawahare R, Wagh A, Warude D, Yeshodharan R
Journal
J Med Chem
Year
2020
PubMed
32368909
Machine-readable
REST APIRDF
Palacky University Olomouc

Palacky University Olomouc

Faculty of Science

Department of Physical Chemistry

tř. 17. listopadu 1192/12

771 46 Olomouc

Czech Republic

How to cite?

Juračka J., Šrejber M., Melíková M., Bazgier V., Berka K.: MolMeDB: Molecules on Membranes Database. Database, Volume 2019, 2019, baz078, https://doi.org/10.1093/database/baz078

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ELIXIRGAČRUP Olomouc
Discovery of Potent, Selective, and State-Dependent Na<sub>V</sub>1.7 Inhibitors with Robust Oral Efficacy in Pain Models: Structure-Activity Relationship and Optimization of Chroman and Indane Aryl Sulfonamides. | MolMeDB