{"data":{"id":3493,"citation":"Ramdas V, Talwar R, Kanoje V, Loriya RM, Banerjee M, Patil P, Joshi AA, Datrange L, Das AK, Walke DS, Kalhapure V, Khan T, Gote G, Dhayagude U, Deshpande S, Shaikh J, Chaure G, Pal RR, Parkale S, Suravase S, Bhoskar S, Gupta RV, Kalia A, Yeshodharan R, Azhar M, Daler J, Mali V, Sharma G, Kishore A, Vyawahare R, Agarwal G, Pareek H, Budhe S, Nayak A, Warude D, Gupta PK, Joshi P, Joshi S, Darekar S, Pandey D, Wagh A, Nigade PB, Mehta M, Patil V, Modi D, Pawar S, Verma M, Verma M, Singh M, Das S, Gundu J, Nemmani K, Bock MG, Sharma S, Bakhle D, Kamboj RK, Palle VP.: Discovery of Potent, Selective, and State-Dependent Na<sub>V<\/sub>1.7 Inhibitors with Robust Oral Efficacy in Pain Models: Structure-Activity Relationship and Optimization of Chroman and Indane Aryl Sulfonamides. J Med Chem, Volume 63 (11), 2020","title":"Discovery of Potent, Selective, and State-Dependent Na<sub>V<\/sub>1.7 Inhibitors with Robust Oral Efficacy in Pain Models: Structure-Activity Relationship and Optimization of Chroman and Indane Aryl Sulfonamides.","doi":"10.1021\/acs.jmedchem.0c00361","doi_url":"https:\/\/doi.org\/10.1021\/acs.jmedchem.0c00361","pmid":"32368909","pmid_url":"https:\/\/pubmed.ncbi.nlm.nih.gov\/32368909\/","year":2020,"journal":"J Med Chem","volume":"63","issue":"11","page":"6107-6133","authors":[{"first_name":"Banerjee M","last_name":null,"full_name":null},{"first_name":"Chaure G","last_name":null,"full_name":null},{"first_name":"Das AK","last_name":null,"full_name":null},{"first_name":"Datrange L","last_name":null,"full_name":null},{"first_name":"Deshpande S","last_name":null,"full_name":null},{"first_name":"Dhayagude U","last_name":null,"full_name":null},{"first_name":"Gote G","last_name":null,"full_name":null},{"first_name":"Joshi AA","last_name":null,"full_name":null},{"first_name":"Kalhapure V","last_name":null,"full_name":null},{"first_name":"Kanoje V","last_name":null,"full_name":null},{"first_name":"Khan T","last_name":null,"full_name":null},{"first_name":"Loriya RM","last_name":null,"full_name":null},{"first_name":"Pal RR","last_name":null,"full_name":null},{"first_name":"Parkale S","last_name":null,"full_name":null},{"first_name":"Patil P","last_name":null,"full_name":null},{"first_name":"Ramdas V","last_name":null,"full_name":null},{"first_name":"Shaikh J","last_name":null,"full_name":null},{"first_name":"Talwar R","last_name":null,"full_name":null},{"first_name":"Walke DS","last_name":null,"full_name":null},{"first_name":"Agarwal G","last_name":null,"full_name":null},{"first_name":"Azhar M","last_name":null,"full_name":null},{"first_name":"Bakhle D","last_name":null,"full_name":null},{"first_name":"Bhoskar S","last_name":null,"full_name":null},{"first_name":"Bock MG","last_name":null,"full_name":null},{"first_name":"Budhe S","last_name":null,"full_name":null},{"first_name":"Daler J","last_name":null,"full_name":null},{"first_name":"Darekar S","last_name":null,"full_name":null},{"first_name":"Das S","last_name":null,"full_name":null},{"first_name":"Gundu J","last_name":null,"full_name":null},{"first_name":"Gupta PK","last_name":null,"full_name":null},{"first_name":"Gupta RV","last_name":null,"full_name":null},{"first_name":"Joshi P","last_name":null,"full_name":null},{"first_name":"Joshi S","last_name":null,"full_name":null},{"first_name":"Kalia A","last_name":null,"full_name":null},{"first_name":"Kamboj RK","last_name":null,"full_name":null},{"first_name":"Kishore A","last_name":null,"full_name":null},{"first_name":"Mali V","last_name":null,"full_name":null},{"first_name":"Mehta M","last_name":null,"full_name":null},{"first_name":"Modi D","last_name":null,"full_name":null},{"first_name":"Nayak A","last_name":null,"full_name":null},{"first_name":"Nemmani K","last_name":null,"full_name":null},{"first_name":"Nigade PB","last_name":null,"full_name":null},{"first_name":"Palle VP.","last_name":null,"full_name":null},{"first_name":"Pandey D","last_name":null,"full_name":null},{"first_name":"Pareek H","last_name":null,"full_name":null},{"first_name":"Patil V","last_name":null,"full_name":null},{"first_name":"Pawar S","last_name":null,"full_name":null},{"first_name":"Sharma G","last_name":null,"full_name":null},{"first_name":"Sharma S","last_name":null,"full_name":null},{"first_name":"Singh M","last_name":null,"full_name":null},{"first_name":"Suravase S","last_name":null,"full_name":null},{"first_name":"Verma M","last_name":null,"full_name":null},{"first_name":"Vyawahare R","last_name":null,"full_name":null},{"first_name":"Wagh A","last_name":null,"full_name":null},{"first_name":"Warude D","last_name":null,"full_name":null},{"first_name":"Yeshodharan R","last_name":null,"full_name":null}],"url":"https:\/\/molmedb.upol.cz\/api\/v1\/publications\/3493","landing_page":"https:\/\/molmedb.upol.cz\/publication\/3493","created_at":"2024-05-21T20:12:16.000000Z","updated_at":null}}