Discovery of cyclic sulfoxide hydroxyethylamines as potent and selective β-site APP-cleaving enzyme 1 (BACE1) inhibitors: structure based design and in vivo reduction of amyloid β-peptides.

Citation: Rueeger H, Lueoend R, Machauer R, Veenstra SJ, Jacobson LH, Staufenbiel M, Desrayaud S, Rondeau JM, Möbitz H, Neumann U.: Discovery of cyclic sulfoxide hydroxyethylamines as potent and selective β-site APP-cleaving enzyme 1 (BACE1) inhibitors: structure based design and in vivo reduction of amyloid β-peptides. Bioorg Med Chem Lett, Volume 23 (19), 2013
Authors: Desrayaud S, Jacobson LH, Lueoend R, Machauer R, Möbitz H, Neumann U., Rondeau JM, Rueeger H, Staufenbiel M, Veenstra SJ
Journal: Bioorg Med Chem Lett
Year: 2013
DOI: 10.1016/j.bmcl.2013.07.071
PubMed: 23981898
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