{"data":{"id":3189,"citation":"Rueeger H, Lueoend R, Machauer R, Veenstra SJ, Jacobson LH, Staufenbiel M, Desrayaud S, Rondeau JM, M\u00f6bitz H, Neumann U.: Discovery of cyclic sulfoxide hydroxyethylamines as potent and selective \u03b2-site APP-cleaving enzyme 1 (BACE1) inhibitors: structure based design and in vivo reduction of amyloid \u03b2-peptides. Bioorg Med Chem Lett, Volume 23 (19), 2013","title":"Discovery of cyclic sulfoxide hydroxyethylamines as potent and selective \u03b2-site APP-cleaving enzyme 1 (BACE1) inhibitors: structure based design and in vivo reduction of amyloid \u03b2-peptides.","doi":"10.1016\/j.bmcl.2013.07.071","doi_url":"https:\/\/doi.org\/10.1016\/j.bmcl.2013.07.071","pmid":"23981898","pmid_url":"https:\/\/pubmed.ncbi.nlm.nih.gov\/23981898\/","year":2013,"journal":"Bioorg Med Chem Lett","volume":"23","issue":"19","page":"5300-5306","authors":[{"first_name":"Desrayaud S","last_name":null,"full_name":null},{"first_name":"Jacobson LH","last_name":null,"full_name":null},{"first_name":"Lueoend R","last_name":null,"full_name":null},{"first_name":"Machauer R","last_name":null,"full_name":null},{"first_name":"M\u00f6bitz H","last_name":null,"full_name":null},{"first_name":"Neumann U.","last_name":null,"full_name":null},{"first_name":"Rondeau JM","last_name":null,"full_name":null},{"first_name":"Rueeger H","last_name":null,"full_name":null},{"first_name":"Staufenbiel M","last_name":null,"full_name":null},{"first_name":"Veenstra SJ","last_name":null,"full_name":null}],"url":"https:\/\/molmedb.upol.cz\/api\/v1\/publications\/3189","landing_page":"https:\/\/molmedb.upol.cz\/publication\/3189","created_at":"2024-05-21T09:16:16.000000Z","updated_at":null}}