Citation

Brodney MA, Barreiro G, Ogilvie K, Hajos-Korcsok E, Murray J, Vajdos F, Ambroise C, Christoffersen C, Fisher K, Lanyon L, Liu J, Nolan CE, Withka JM, Borzilleri KA, Efremov I, Oborski CE, Varghese A, O'Neill BT.: Spirocyclic sulfamides as β-secretase 1 (BACE-1) inhibitors for the treatment of Alzheimer's disease: utilization of structure based drug design, WaterMap, and CNS penetration studies to identify centrally efficacious inhibitors. J Med Chem, Volume 55 (21), 2012

Authors

Ambroise C, Barreiro G, Borzilleri KA, Brodney MA, Christoffersen C, Efremov I, Fisher K, Hajos-Korcsok E, Lanyon L, Liu J, Murray J, Nolan CE, O'Neill BT., Oborski CE, Ogilvie K, Vajdos F, Varghese A, Withka JM

Journal

J Med Chem

Year

2012

DOI

10.1021/jm3009426

PubMed

22984865

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