Scaffold-Hopping and Structure-Based Discovery of Potent, Selective, And Brain Penetrant N-(1H-Pyrazol-3-yl)pyridin-2-amine Inhibitors of Dual Leucine Zipper Kinase (DLK, MAP3K12).

Citation: Patel S, Harris SF, Gibbons P, Deshmukh G, Gustafson A, Kellar T, Lin H, Liu X, Liu Y, Liu Y, Ma C, Scearce-Levie K, Ghosh AS, Shin YG, Solanoy H, Wang J, Wang B, Yin J, Siu M, Lewcock JW.: Scaffold-Hopping and Structure-Based Discovery of Potent, Selective, And Brain Penetrant N-(1H-Pyrazol-3-yl)pyridin-2-amine Inhibitors of Dual Leucine Zipper Kinase (DLK, MAP3K12). J Med Chem, Volume 58 (20), 2015
Authors: Deshmukh G, Ghosh AS, Gibbons P, Gustafson A, Harris SF, Kellar T, Lewcock JW., Lin H, Liu X, Liu Y, Ma C, Patel S, Scearce-Levie K, Shin YG, Siu M, Solanoy H, Wang B, Wang J, Yin J
Journal: J Med Chem
Year: 2015
DOI: 10.1021/acs.jmedchem.5b01072
PubMed: 26431428
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