Citation

Wang X, Liu B, Searle X, Yeung C, Bogdan A, Greszler S, Singh A, Fan Y, Swensen AM, Vortherms T, Balut C, Jia Y, Desino K, Gao W, Yong H, Tse C, Kym P.: Discovery of 4-[(2R,4R)-4-({[1-(2,2-Difluoro-1,3-benzodioxol-5-yl)cyclopropyl]carbonyl}amino)-7-(difluoromethoxy)-3,4-dihydro-2H-chromen-2-yl]benzoic Acid (ABBV/GLPG-2222), a Potent Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Corrector for the Treatment of Cystic Fibrosis. J Med Chem, Volume 61 (4), 2018

Authors

Balut C, Bogdan A, Desino K, Fan Y, Gao W, Greszler S, Jia Y, Kym P., Liu B, Searle X, Singh A, Swensen AM, Tse C, Vortherms T, Wang X, Yeung C, Yong H

Journal

J Med Chem

Year

2018

DOI

10.1021/acs.jmedchem.7b01339

PubMed

29251932

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