Citation

Kawada H, Ebiike H, Tsukazaki M, Yamamoto S, Koyama K, Nakamura M, Morikami K, Yoshinari K, Yoshida M, Ogawa K, Shimma N, Tsukuda T, Ohwada J.: Optimization of the phenylurea moiety in a phosphoinositide 3-kinase (PI3K) inhibitor to improve water solubility and the PK profile by introducing a solubilizing group and ortho substituents. Bioorg Med Chem, Volume 24 (13), 2016

Authors

Ebiike H, Kawada H, Koyama K, Morikami K, Nakamura M, Ogawa K, Ohwada J., Shimma N, Tsukazaki M, Tsukuda T, Yamamoto S, Yoshida M, Yoshinari K

Journal

Bioorg Med Chem

Year

2016

DOI

10.1016/j.bmc.2016.04.060

PubMed

27189888

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