Citation

Lu T, Markotan T, Ballentine SK, Giardino EC, Spurlino J, Crysler CS, Brown K, Maryanoff BE, Tomczuk BE, Damiano BP, Shukla U, End D, Andrade-Gordon P, Bone RF, Player MR.: Discovery and clinical evaluation of 1-{N-[2-(amidinoaminooxy)ethyl]amino}carbonylmethyl-6-methyl-3-[2,2-difluoro-2-phenylethylamino]pyrazinone (RWJ-671818), a thrombin inhibitor with an oxyguanidine P1 motif. J Med Chem, Volume 53 (4), 2010

Authors

Andrade-Gordon P, Ballentine SK, Bone RF, Brown K, Crysler CS, Damiano BP, End D, Giardino EC, Lu T, Markotan T, Maryanoff BE, Player MR., Shukla U, Spurlino J, Tomczuk BE

Journal

J Med Chem

Year

2010

DOI

10.1021/jm901802n

PubMed

20102150

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