Citation

Hadida S, Van Goor F, Zhou J, Arumugam V, McCartney J, Hazlewood A, Decker C, Negulescu P, Grootenhuis PD.: Discovery of N-(2,4-di-tert-butyl-5-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide (VX-770, ivacaftor), a potent and orally bioavailable CFTR potentiator. J Med Chem, Volume 57 (23), 2014

Authors

Arumugam V, Decker C, Grootenhuis PD., Hadida S, Hazlewood A, McCartney J, Negulescu P, Van Goor F, Zhou J

Journal

J Med Chem

Year

2014

DOI

10.1021/jm5012808

PubMed

25441013

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