cis-4-(Piperazin-1-yl)-5,6,7a,8,9,10,11,11a-octahydrobenzofuro[2,3-h]quinazolin-2-amine (A-987306), a new histamine H4R antagonist that blocks pain responses against carrageenan-induced hyperalgesia.

Citation: Liu H, Altenbach RJ, Carr TL, Chandran P, Hsieh GC, Lewis LG, Manelli AM, Milicic I, Marsh KC, Miller TR, Strakhova MI, Vortherms TA, Wakefield BD, Wetter JM, Witte DG, Honore P, Esbenshade TA, Brioni JD, Cowart MD.: cis-4-(Piperazin-1-yl)-5,6,7a,8,9,10,11,11a-octahydrobenzofuro[2,3-h]quinazolin-2-amine (A-987306), a new histamine H4R antagonist that blocks pain responses against carrageenan-induced hyperalgesia. J Med Chem, Volume 51 (22), 2008
Authors: Altenbach RJ, Brioni JD, Carr TL, Chandran P, Cowart MD., Esbenshade TA, Honore P, Hsieh GC, Lewis LG, Liu H, Manelli AM, Marsh KC, Milicic I, Miller TR, Strakhova MI, Vortherms TA, Wakefield BD, Wetter JM, Witte DG
Journal: J Med Chem
Year: 2008
DOI: 10.1021/jm8007618
PubMed: 18983139
Machine-readable: REST API RDF

Publication