Design of Conformationally Constrained Acyl Sulfonamide Isosteres: Identification of N-([1,2,4]Triazolo[4,3- a]pyridin-3-yl)methane-sulfonamides as Potent and Selective hNaV1.7 Inhibitors for the Treatment of Pain.

Publication

Citation
Focken T, Chowdhury S, Zenova A, Grimwood ME, Chabot C, Sheng T, Hemeon I, Decker SM, Wilson M, Bichler P, Jia Q, Sun S, Young C, Lin S, Goodchild SJ, Shuart NG, Chang E, Xie Z, Li B, Khakh K, Bankar G, Waldbrook M, Kwan R, Nelkenbrecher K, Karimi Tari P, Chahal N, Sojo L, Robinette CL, White AD, Chen CA, Zhang Y, Pang J, Chang JH, Hackos DH, Johnson JP, Cohen CJ, Ortwine DF, Sutherlin DP, Dehnhardt CM, Safina BS.: Design of Conformationally Constrained Acyl Sulfonamide Isosteres: Identification of N-([1,2,4]Triazolo[4,3- a]pyridin-3-yl)methane-sulfonamides as Potent and Selective hNaV1.7 Inhibitors for the Treatment of Pain. J Med Chem, Volume 61 (11), 2018
Authors
Bankar G, Bichler P, Chabot C, Chahal N, Chang E, Chang JH, Chen CA, Chowdhury S, Decker SM, Focken T, Goodchild SJ, Grimwood ME, Hackos DH, Hemeon I, Jia Q, Karimi Tari P, Khakh K, Kwan R, Li B, Lin S, Nelkenbrecher K, Pang J, Robinette CL, Sheng T, Shuart NG, Sojo L, Sun S, Waldbrook M, White AD, Wilson M, Xie Z, Young C, Zenova A, Zhang Y, Cohen CJ, Dehnhardt CM, Johnson JP, Ortwine DF, Safina BS., Sutherlin DP
Journal
J Med Chem
Year
2018
PubMed
29737846
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Palacky University Olomouc

Palacky University Olomouc

Faculty of Science

Department of Physical Chemistry

tř. 17. listopadu 1192/12

771 46 Olomouc

Czech Republic

How to cite?

Juračka J., Šrejber M., Melíková M., Bazgier V., Berka K.: MolMeDB: Molecules on Membranes Database. Database, Volume 2019, 2019, baz078, https://doi.org/10.1093/database/baz078

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