Citation

Ruggeri R., Buckbinder L., Bagley S., Carpino P., Conn E., Dowling M., Fernando D., Jiao W., Kung D., Orr S., Qi Y., Rocke B., Smith A., Warmus J., Zhang Y., Bowles D., Widlicka D., Eng H., Ryder T., Sharma R., Wolford A., Okerberg C., Walters K., Maurer T., Zhang Y., Bonin P., Spath S., Xing G., Hepworth D., Ahn K., Kalgutkar A.: Discovery of 2-(6-(5-Chloro-2-methoxyphenyl)-4-oxo-2-thioxo-3,4-dihydropyrimidin-1(2<i>H</i>)-yl)acetamide (PF-06282999): A Highly Selective Mechanism-Based Myeloperoxidase Inhibitor for the Treatment of Cardiovascular Diseases. Journal of Medicinal Chemistry, Volume 58 (21), 2015

Authors

Roger B. Ruggeri, Leonard Buckbinder, Scott W. Bagley, Philip A. Carpino, Edward L. Conn, Matthew S. Dowling, Dilinie P. Fernando, Wenhua Jiao, Daniel W. Kung, Suvi T. M. Orr, Yingmei Qi, Benjamin N. Rocke, Aaron Smith, Joseph S. Warmus, Yan Zhang, Daniel Bowles, Daniel W. Widlicka, Heather Eng, Tim Ryder, Raman Sharma, Angela Wolford, Carlin Okerberg, Karen Walters, Tristan S. Maurer, Yanwei Zhang, Paul D. Bonin, Samantha N. Spath, Gang Xing, David Hepworth, Kay Ahn, Amit S. Kalgutkar

Journal

Journal of Medicinal Chemistry

Year

2015

DOI

10.1021/acs.jmedchem.5b00963

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