Discovery of (<i>S</i>)-6-(3-Cyclopentyl-2-(4-(trifluoromethyl)-1<i>H</i>-imidazol-1-yl)propanamido)nicotinic Acid as a Hepatoselective Glucokinase Activator Clinical Candidate for Treating Type 2 Diabetes Mellitus

Publication

Citation
Pfefferkorn J., Guzman-Perez A., Litchfield J., Aiello R., Treadway J., Pettersen J., Minich M., Filipski K., Jones C., Tu M., Aspnes G., Risley H., Bian J., Stevens B., Bourassa P., D’Aquila T., Baker L., Barucci N., Robertson A., Bourbonais F., Derksen D., MacDougall M., Cabrera O., Chen J., Lapworth A., Landro J., Zavadoski W., Atkinson K., Haddish-Berhane N., Tan B., Yao L., Kosa R., Varma M., Feng B., Duignan D., El-Kattan A., Murdande S., Liu S., Ammirati M., Knafels J., DaSilva-Jardine P., Sweet L., Liras S., Rolph T.: Discovery of (<i>S</i>)-6-(3-Cyclopentyl-2-(4-(trifluoromethyl)-1<i>H</i>-imidazol-1-yl)propanamido)nicotinic Acid as a Hepatoselective Glucokinase Activator Clinical Candidate for Treating Type 2 Diabetes Mellitus. Journal of Medicinal Chemistry, Volume 55 (3), 2012
Authors
Jeffrey A. Pfefferkorn, Angel Guzman-Perez, John Litchfield, Robert Aiello, Judith L. Treadway, John Pettersen, Martha L. Minich, Kevin J. Filipski, Christopher S. Jones, Meihua Tu, Gary Aspnes, Hud Risley, Jianwei Bian, Benjamin D. Stevens, Patricia Bourassa, Theresa D’Aquila, Levenia Baker, Nicole Barucci, Alan S. Robertson, Francis Bourbonais, David R. Derksen, Margit MacDougall, Over Cabrera, Jing Chen, Amanda Lee Lapworth, James A. Landro, William J. Zavadoski, Karen Atkinson, Nahor Haddish-Berhane, Beijing Tan, Lili Yao, Rachel E. Kosa, Manthena V. Varma, Bo Feng, David B. Duignan, Ayman El-Kattan, Sharad Murdande, Shenping Liu, Mark Ammirati, John Knafels, Paul DaSilva-Jardine, Laurel Sweet, Spiros Liras, Timothy P. Rolph
Journal
Journal of Medicinal Chemistry
Year
2012
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Palacky University Olomouc

Palacky University Olomouc

Faculty of Science

Department of Physical Chemistry

tř. 17. listopadu 1192/12

771 46 Olomouc

Czech Republic

How to cite?

Juračka J., Šrejber M., Melíková M., Bazgier V., Berka K.: MolMeDB: Molecules on Membranes Database. Database, Volume 2019, 2019, baz078, https://doi.org/10.1093/database/baz078

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