Late-Stage Lead Diversification Coupled with Quantitative Nuclear Magnetic Resonance Spectroscopy to Identify New Structure–Activity Relationship Vectors at Nanomole-Scale Synthesis: Application to Loratadine, a Human Histamine H <sub>1</sub> Receptor Inverse Agonist

Publication

Citation
Lall M., Bassyouni A., Bradow J., Brown M., Bundesmann M., Chen J., Ciszewski G., Hagen A., Hyek D., Jenkinson S., Liu B., Obach R., Pan S., Reilly U., Sach N., Smaltz D., Spracklin D., Starr J., Wagenaar M., Walker G.: Late-Stage Lead Diversification Coupled with Quantitative Nuclear Magnetic Resonance Spectroscopy to Identify New Structure–Activity Relationship Vectors at Nanomole-Scale Synthesis: Application to Loratadine, a Human Histamine H <sub>1</sub> Receptor Inverse Agonist. Journal of Medicinal Chemistry, Volume 63 (13), 2020
Authors
Manjinder S. Lall, Asser Bassyouni, James Bradow, Maria Brown, Mark Bundesmann, Jinshan Chen, Gregory Ciszewski, Anne E. Hagen, Dennis Hyek, Stephen Jenkinson, Bo Liu, R. Scott Obach, Senliang Pan, Usa Reilly, Neal Sach, Daniel J. Smaltz, Douglas K. Spracklin, Jeremy Starr, Melissa Wagenaar, Gregory S. Walker
Journal
Journal of Medicinal Chemistry
Year
2020
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Palacky University Olomouc

Palacky University Olomouc

Faculty of Science

Department of Physical Chemistry

tř. 17. listopadu 1192/12

771 46 Olomouc

Czech Republic

How to cite?

Juračka J., Šrejber M., Melíková M., Bazgier V., Berka K.: MolMeDB: Molecules on Membranes Database. Database, Volume 2019, 2019, baz078, https://doi.org/10.1093/database/baz078

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