Citation

O’Neill B., Beck E., Butler C., Nolan C., Gonzales C., Zhang L., Doran S., Lapham K., Buzon L., Dutra J., Barreiro G., Hou X., Martinez-Alsina L., Rogers B., Villalobos A., Murray J., Ogilvie K., LaChapelle E., Chang C., Lanyon L., Steppan C., Robshaw A., Hales K., Boucher G., Pandher K., Houle C., Ambroise C., Karanian D., Riddell D., Bales K., Brodney M.: Design and Synthesis of Clinical Candidate PF-06751979: A Potent, Brain Penetrant, β-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitor Lacking Hypopigmentation. Journal of Medicinal Chemistry, Volume 61 (10), 2018

Authors

Brian T. O’Neill, Elizabeth M. Beck, Christopher R. Butler, Charles E. Nolan, Cathleen Gonzales, Lei Zhang, Shawn D. Doran, Kimberly Lapham, Leanne M. Buzon, Jason K. Dutra, Gabriela Barreiro, Xinjun Hou, Luis A. Martinez-Alsina, Bruce N. Rogers, Anabella Villalobos, John C. Murray, Kevin Ogilvie, Erik A. LaChapelle, Cheng Chang, Lorraine F. Lanyon, Claire M. Steppan, Ashley Robshaw, Katherine Hales, Germaine G. Boucher, Karamjeet Pandher, Christopher Houle, Claude W. Ambroise, David Karanian, David Riddell, Kelly R. Bales, Michael A. Brodney

Journal

Journal of Medicinal Chemistry

Year

2018

DOI

10.1021/acs.jmedchem.8b00246

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