Citation

Zhang L., Balan G., Barreiro G., Boscoe B., Chenard L., Cianfrogna J., Claffey M., Chen L., Coffman K., Drozda S., Dunetz J., Fonseca K., Galatsis P., Grimwood S., Lazzaro J., Mancuso J., Miller E., Reese M., Rogers B., Sakurada I., Skaddan M., Smith D., Stepan A., Trapa P., Tuttle J., Verhoest P., Walker D., Wright A., Zaleska M., Zasadny K., Shaffer C.: Discovery and Preclinical Characterization of 1-Methyl-3-(4-methylpyridin-3-yl)-6-(pyridin-2-ylmethoxy)-1 <i>H</i> -pyrazolo-[3,4- <i>b</i> ]pyrazine (PF470): A Highly Potent, Selective, and Efficacious Metabotropic Glutamate Receptor 5 (mGluR5) Negative Allosteric Modulator. Journal of Medicinal Chemistry, Volume 57 (3), 2014

Authors

Lei Zhang, Gayatri Balan, Gabriela Barreiro, Brian P. Boscoe, Lois K. Chenard, Julie Cianfrogna, Michelle M. Claffey, Laigao Chen, Karen J. Coffman, Susan E. Drozda, Joshua R. Dunetz, Kari R. Fonseca, Paul Galatsis, Sarah Grimwood, John T. Lazzaro, Jessica Y. Mancuso, Emily L. Miller, Matthew R. Reese, Bruce N. Rogers, Isao Sakurada, Marc Skaddan, Deborah L. Smith, Antonia F. Stepan, Patrick Trapa, Jamison B. Tuttle, Patrick R. Verhoest, Daniel P. Walker, Ann S. Wright, Margaret M. Zaleska, Kenneth Zasadny, Christopher L. Shaffer

Journal

Journal of Medicinal Chemistry

Year

2014

DOI

10.1021/jm401622k

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