Citation

Mainolfi N, Ehara T, Karki RG, Anderson K, Mac Sweeney A, Liao SM, Argikar UA, Jendza K, Zhang C, Powers J, Klosowski DW, Crowley M, Kawanami T, Ding J, April M, Forster C, Serrano-Wu M, Capparelli M, Ramqaj R, Solovay C, Cumin F, Smith TM, Ferrara L, Lee W, Long D, Prentiss M, De Erkenez A, Yang L, Liu F, Sellner H, Sirockin F, Valeur E, Erbel P, Ostermeier D, Ramage P, Gerhartz B, Schubart A, Flohr S, Gradoux N, Feifel R, Vogg B, Wiesmann C, Maibaum J, Eder J, Sedrani R, Harrison RA, Mogi M, Jaffee BD, Adams CM.: Discovery of 4-((2<i>S</i>,4<i>S</i>)-4-Ethoxy-1-((5-methoxy-7-methyl-1<i>H</i>-indol-4-yl)methyl)piperidin-2-yl)benzoic Acid (LNP023), a Factor B Inhibitor Specifically Designed To Be Applicable to Treating a Diverse Array of Complement Mediated Diseases. J Med Chem, Volume 63 (11), 2020

Authors

Anderson K, April M, Argikar UA, Capparelli M, Crowley M, Cumin F, De Erkenez A, Ding J, Ehara T, Erbel P, Ferrara L, Forster C, Jendza K, Karki RG, Kawanami T, Klosowski DW, Lee W, Liao SM, Liu F, Long D, Mac Sweeney A, Mainolfi N, Ostermeier D, Powers J, Prentiss M, Ramqaj R, Sellner H, Serrano-Wu M, Sirockin F, Smith TM, Solovay C, Valeur E, Yang L, Zhang C, Adams CM., Eder J, Feifel R, Flohr S, Gerhartz B, Gradoux N, Harrison RA, Jaffee BD, Maibaum J, Mogi M, Ramage P, Schubart A, Sedrani R, Vogg B, Wiesmann C

Journal

J Med Chem

Year

2020

DOI

10.1021/acs.jmedchem.9b01870

PubMed

32073845

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