Citation

Mandal M, Zhu Z, Cumming JN, Liu X, Strickland C, Mazzola RD, Caldwell JP, Leach P, Grzelak M, Hyde L, Zhang Q, Terracina G, Zhang L, Chen X, Kuvelkar R, Kennedy ME, Favreau L, Cox K, Orth P, Buevich A, Voigt J, Wang H, Kazakevich I, McKittrick BA, Greenlee W, Parker EM, Stamford AW.: Design and validation of bicyclic iminopyrimidinones as beta amyloid cleaving enzyme-1 (BACE1) inhibitors: conformational constraint to favor a bioactive conformation. J Med Chem, Volume 55 (21), 2012

Authors

Buevich A, Caldwell JP, Chen X, Cox K, Cumming JN, Favreau L, Greenlee W, Grzelak M, Hyde L, Kazakevich I, Kennedy ME, Kuvelkar R, Leach P, Liu X, Mandal M, Mazzola RD, McKittrick BA, Orth P, Parker EM, Stamford AW., Strickland C, Terracina G, Voigt J, Wang H, Zhang L, Zhang Q, Zhu Z

Journal

J Med Chem

Year

2012

DOI

10.1021/jm301039c

PubMed

22989333

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