Citation

Knegtel R, Charrier JD, Durrant S, Davis C, O'Donnell M, Storck P, MacCormick S, Kay D, Pinder J, Virani A, Twin H, Griffiths M, Reaper P, Littlewood P, Young S, Golec J, Pollard J.: Rational Design of 5-(4-(Isopropylsulfonyl)phenyl)-3-(3-(4-((methylamino)methyl)phenyl)isoxazol-5-yl)pyrazin-2-amine (VX-970, M6620): Optimization of Intra- and Intermolecular Polar Interactions of a New Ataxia Telangiectasia Mutated and Rad3-Related (ATR) Kinase Inhibitor. J Med Chem, Volume 62 (11), 2019

Authors

Charrier JD, Davis C, Durrant S, Golec J, Griffiths M, Kay D, Knegtel R, Littlewood P, MacCormick S, O'Donnell M, Pinder J, Pollard J., Reaper P, Storck P, Twin H, Virani A, Young S

Journal

J Med Chem

Year

2019

DOI

10.1021/acs.jmedchem.9b00426

PubMed

31074988

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