Citation

Kosugi T, Mitchell DR, Fujino A, Imai M, Kambe M, Kobayashi S, Makino H, Matsueda Y, Oue Y, Komatsu K, Imaizumi K, Sakai Y, Sugiura S, Takenouchi O, Unoki G, Yamakoshi Y, Cunliffe V, Frearson J, Gordon R, Harris CJ, Kalloo-Hosein H, Le J, Patel G, Simpson DJ, Sherborne B, Thomas PS, Suzuki N, Takimoto-Kamimura M, Kataoka K.: Mitogen-activated protein kinase-activated protein kinase 2 (MAPKAP-K2) as an antiinflammatory target: discovery and in vivo activity of selective pyrazolo[1,5-a]pyrimidine inhibitors using a focused library and structure-based optimization approach. J Med Chem, Volume 55 (15), 2012

Authors

Cunliffe V, Frearson J, Fujino A, Gordon R, Harris CJ, Imai M, Imaizumi K, Kalloo-Hosein H, Kambe M, Kataoka K., Kobayashi S, Komatsu K, Kosugi T, Le J, Makino H, Matsueda Y, Mitchell DR, Oue Y, Patel G, Sakai Y, Sherborne B, Simpson DJ, Sugiura S, Suzuki N, Takenouchi O, Takimoto-Kamimura M, Thomas PS, Unoki G, Yamakoshi Y

Journal

J Med Chem

Year

2012

DOI

10.1021/jm300411k

PubMed

22746295

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