Discovery of SAR184841, a potent and long-lasting inhibitor of 11β-hydroxysteroid dehydrogenase type 1, active in a physiopathological animal model of T2D.

Citation: Venier O, Pascal C, Braun A, Namane C, Mougenot P, Crespin O, Pacquet F, Mougenot C, Monseau C, Onofri B, Dadji-Faïhun R, Leger C, Ben-Hassine M, Van-Pham T, Ragot JL, Philippo C, Farjot G, Noah L, Maniani K, Boutarfa A, Nicolaï E, Guillot E, Pruniaux MP, Güssregen S, Engel C, Coutant AL, de Miguel B, Castro A.: Discovery of SAR184841, a potent and long-lasting inhibitor of 11β-hydroxysteroid dehydrogenase type 1, active in a physiopathological animal model of T2D. Bioorg Med Chem Lett, Volume 23 (8), 2013
Authors: Ben-Hassine M, Boutarfa A, Braun A, Castro A., Coutant AL, Crespin O, Dadji-Faïhun R, de Miguel B, Engel C, Farjot G, Guillot E, Güssregen S, Leger C, Maniani K, Monseau C, Mougenot C, Mougenot P, Namane C, Nicolaï E, Noah L, Onofri B, Pacquet F, Pascal C, Philippo C, Pruniaux MP, Ragot JL, Van-Pham T, Venier O
Journal: Bioorg Med Chem Lett
Year: 2013
DOI: 10.1016/j.bmcl.2013.02.018
PubMed: 23478147
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