Potent Antimalarials with Development Potential Identified by Structure-Guided Computational Optimization of a Pyrrole-Based Dihydroorotate Dehydrogenase Inhibitor Series.

Publication

Citation
Palmer MJ, Deng X, Watts S, Krilov G, Gerasyuto A, Kokkonda S, El Mazouni F, White J, White KL, Striepen J, Bath J, Schindler KA, Yeo T, Shackleford DM, Mok S, Deni I, Lawong A, Huang A, Chen G, Wang W, Jayaseelan J, Katneni K, Patil R, Saunders J, Shahi SP, Chittimalla R, Angulo-Barturen I, Jiménez-Díaz MB, Wittlin S, Tumwebaze PK, Rosenthal PJ, Cooper RA, Aguiar ACC, Guido RVC, Pereira DB, Mittal N, Winzeler EA, Tomchick DR, Laleu B, Burrows JN, Rathod PK, Fidock DA, Charman SA, Phillips MA.: Potent Antimalarials with Development Potential Identified by Structure-Guided Computational Optimization of a Pyrrole-Based Dihydroorotate Dehydrogenase Inhibitor Series. J Med Chem, Volume 64 (9), 2021
Authors
Aguiar ACC, Angulo-Barturen I, Bath J, Burrows JN, Charman SA, Chen G, Chittimalla R, Cooper RA, Deng X, Deni I, El Mazouni F, Fidock DA, Gerasyuto A, Guido RVC, Huang A, Jayaseelan J, Jiménez-Díaz MB, Katneni K, Kokkonda S, Krilov G, Laleu B, Lawong A, Mittal N, Mok S, Palmer MJ, Patil R, Pereira DB, Phillips MA., Rathod PK, Rosenthal PJ, Saunders J, Schindler KA, Shackleford DM, Shahi SP, Striepen J, Tomchick DR, Tumwebaze PK, Wang W, Watts S, White J, White KL, Winzeler EA, Wittlin S, Yeo T
Journal
J Med Chem
Year
2021
PubMed
33876936
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Palacky University Olomouc

Palacky University Olomouc

Faculty of Science

Department of Physical Chemistry

tř. 17. listopadu 1192/12

771 46 Olomouc

Czech Republic

How to cite?

Juračka J., Šrejber M., Melíková M., Bazgier V., Berka K.: MolMeDB: Molecules on Membranes Database. Database, Volume 2019, 2019, baz078, https://doi.org/10.1093/database/baz078

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