Use of Intramolecular 1,5-Sulfur-Oxygen and 1,5-Sulfur-Halogen Interactions in the Design of N-Methyl-5-aryl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine SMN2 Splicing Modulators.

Citation: Axford J, Sung MJ, Manchester J, Chin D, Jain M, Shin Y, Dix I, Hamann LG, Cheung AK, Sivasankaran R, Briner K, Dales NA, Hurley B.: Use of Intramolecular 1,5-Sulfur-Oxygen and 1,5-Sulfur-Halogen Interactions in the Design of N-Methyl-5-aryl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine SMN2 Splicing Modulators. J Med Chem, Volume 64 (8), 2021
Authors: Axford J, Briner K, Cheung AK, Chin D, Dales NA, Dix I, Hamann LG, Hurley B., Jain M, Manchester J, Shin Y, Sivasankaran R, Sung MJ
Journal: J Med Chem
Year: 2021
DOI: 10.1021/acs.jmedchem.0c02173
PubMed: 33822618
Machine-readable: REST API RDF

Use of Intramolecular 1,5-Sulfur-Oxygen and 1,5-Sulfur-Halogen Interactions in the Design of <i>N</i>-Methyl-5-aryl-<i>N</i>-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine SMN2 Splicing Modulators.