N-[6-(4-butanoyl-5-methyl-1H-pyrazol-1-yl)pyridazin-3-yl]-5-chloro-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]-1H-indole-3-carboxamide (SAR216471), a novel intravenous and oral, reversible, and directly acting P2Y12 antagonist.

Citation: Boldron C, Besse A, Bordes MF, Tissandié S, Yvon X, Gau B, Badorc A, Rousseaux T, Barré G, Meneyrol J, Zech G, Nazare M, Fossey V, Pflieger AM, Bonnet-Lignon S, Millet L, Briot C, Dol F, Hérault JP, Savi P, Lassalle G, Delesque N, Herbert JM, Bono F.: N-[6-(4-butanoyl-5-methyl-1H-pyrazol-1-yl)pyridazin-3-yl]-5-chloro-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]-1H-indole-3-carboxamide (SAR216471), a novel intravenous and oral, reversible, and directly acting P2Y12 antagonist. J Med Chem, Volume 57 (17), 2014
Authors: Badorc A, Barré G, Besse A, Boldron C, Bonnet-Lignon S, Bono F., Bordes MF, Briot C, Delesque N, Dol F, Fossey V, Gau B, Hérault JP, Herbert JM, Lassalle G, Meneyrol J, Millet L, Nazaré M, Pflieger AM, Rousseaux T, Savi P, Tissandié S, Yvon X, Zech G
Journal: J Med Chem
Year: 2014
DOI: 10.1021/jm500588w
PubMed: 25075638
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