Discovery, Structure-Activity Relationships, and In Vivo Evaluation of Novel Aryl Amides as Brain Penetrant Adaptor Protein 2-Associated Kinase 1 (AAK1) Inhibitors for the Treatment of Neuropathic Pain.

Citation: Hartz RA, Ahuja VT, Nara SJ, Kumar CMV, Brown JM, Bristow LJ, Rajamani R, Muckelbauer JK, Camac D, Kiefer SE, Hunihan L, Gulianello M, Lewis M, Easton A, Lippy JS, Surti N, Pattipati SN, Dokania M, Elavazhagan S, Dandapani K, Hamman BD, Allen J, Kostich W, Bronson JJ, Macor JE, Dzierba CD.: Discovery, Structure-Activity Relationships, and In Vivo Evaluation of Novel Aryl Amides as Brain Penetrant Adaptor Protein 2-Associated Kinase 1 (AAK1) Inhibitors for the Treatment of Neuropathic Pain. J Med Chem, Volume 64 (15), 2021
Authors: Ahuja VT, Allen J, Bristow LJ, Bronson JJ, Brown JM, Camac D, Dandapani K, Dokania M, Dzierba CD., Easton A, Elavazhagan S, Gulianello M, Hamman BD, Hartz RA, Hunihan L, Kiefer SE, Kostich W, Kumar CMV, Lewis M, Lippy JS, Macor JE, Muckelbauer JK, Nara SJ, Pattipati SN, Rajamani R, Surti N
Journal: J Med Chem
Year: 2021
DOI: 10.1021/acs.jmedchem.1c00472
PubMed: 34270254
Machine-readable: REST API RDF

Publication