Citation

Mandal M, Wu Y, Misiaszek J, Li G, Buevich A, Caldwell JP, Liu X, Mazzola RD, Orth P, Strickland C, Voigt J, Wang H, Zhu Z, Chen X, Grzelak M, Hyde LA, Kuvelkar R, Leach PT, Terracina G, Zhang L, Zhang Q, Michener MS, Smith B, Cox K, Grotz D, Favreau L, Mitra K, Kazakevich I, McKittrick BA, Greenlee W, Kennedy ME, Parker EM, Cumming JN, Stamford AW.: Structure-Based Design of an Iminoheterocyclic β-Site Amyloid Precursor Protein Cleaving Enzyme (BACE) Inhibitor that Lowers Central Aβ in Nonhuman Primates. J Med Chem, Volume 59 (7), 2016

Authors

Buevich A, Caldwell JP, Chen X, Cox K, Cumming JN, Favreau L, Greenlee W, Grotz D, Grzelak M, Hyde LA, Kazakevich I, Kennedy ME, Kuvelkar R, Leach PT, Li G, Liu X, Mandal M, Mazzola RD, McKittrick BA, Michener MS, Misiaszek J, Mitra K, Orth P, Parker EM, Smith B, Stamford AW., Strickland C, Terracina G, Voigt J, Wang H, Wu Y, Zhang L, Zhang Q, Zhu Z

Journal

J Med Chem

Year

2016

DOI

10.1021/acs.jmedchem.5b01995

PubMed

26937601

Machine-readable

REST APIRDF