Identification of a Novel 2,8-Diazaspiro[4.5]decan-1-one Derivative as a Potent and Selective Dual TYK2/JAK1 Inhibitor for the Treatment of Inflammatory Bowel Disease.

Citation: Yang T, Cui X, Tang M, Qi W, Zhu Z, Shi M, Yang L, Pei H, Zhang W, Xie L, Xu Y, Yang Z, Chen L.: Identification of a Novel 2,8-Diazaspiro[4.5]decan-1-one Derivative as a Potent and Selective Dual TYK2/JAK1 Inhibitor for the Treatment of Inflammatory Bowel Disease. J Med Chem, Volume 65 (4), 2022
Authors: Chen L., Cui X, Pei H, Qi W, Shi M, Tang M, Xie L, Xu Y, Yang L, Yang T, Yang Z, Zhang W, Zhu Z
Journal: J Med Chem
Year: 2022
DOI: 10.1021/acs.jmedchem.1c01137
PubMed: 35113547
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