Benzimidazole inhibitors induce a DFG-out conformation of never in mitosis gene A-related kinase 2 (Nek2) without binding to the back pocket and reveal a nonlinear structure-activity relationship.

Citation: Solanki S, Innocenti P, Mas-Droux C, Boxall K, Barillari C, van Montfort RL, Aherne GW, Bayliss R, Hoelder S.: Benzimidazole inhibitors induce a DFG-out conformation of never in mitosis gene A-related kinase 2 (Nek2) without binding to the back pocket and reveal a nonlinear structure-activity relationship. J Med Chem, Volume 54 (6), 2011
Authors: Aherne GW, Barillari C, Bayliss R, Boxall K, Hoelder S., Innocenti P, Mas-Droux C, Solanki S, van Montfort RL
Journal: J Med Chem
Year: 2011
DOI: 10.1021/jm1011726
PubMed: 21366329
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