Synthesis and optimization of 4,5,6,7-tetrahydrooxazolo[4,5-c]pyridines as potent and orally-active metabotropic glutamate receptor 5 negative allosteric modulators.

Citation: Hirose W, Kato Y, Natsutani I, Takata M, Kitaichi M, Imai S, Hayashi S, Arai Y, Hoshino K, Yoshida K.: Synthesis and optimization of 4,5,6,7-tetrahydrooxazolo[4,5-c]pyridines as potent and orally-active metabotropic glutamate receptor 5 negative allosteric modulators. Bioorg Med Chem Lett, Volume 27 (18), 2017
Authors: Arai Y, Hayashi S, Hirose W, Hoshino K, Imai S, Kato Y, Kitaichi M, Natsutani I, Takata M, Yoshida K.
Journal: Bioorg Med Chem Lett
Year: 2017
DOI: 10.1016/j.bmcl.2017.08.030
PubMed: 28838696
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