Citation

Hughes RO, Walker JK, Rogier DJ, Heasley SE, Blevis-Bal RM, Benson AG, Jacobsen EJ, Cubbage JW, Fobian YM, Owen DR, Freskos JN, Molyneaux JM, Brown DL, Acker BA, Maddux TM, Tollefson MB, Moon JB, Mischke BV, Rumsey JM, Zheng Y, MacInnes A, Bond BR, Yu Y.: Optimization of the aminopyridopyrazinones class of PDE5 inhibitors: discovery of 3-[(trans-4-hydroxycyclohexyl)amino]-7-(6-methoxypyridin-3-yl)-1-(2-propoxyethyl)pyrido[3,4-b]pyrazin-2(1H)-one. Bioorg Med Chem Lett, Volume 19 (17), 2009

Authors

Acker BA, Benson AG, Blevis-Bal RM, Brown DL, Cubbage JW, Fobian YM, Freskos JN, Heasley SE, Hughes RO, Jacobsen EJ, Maddux TM, Mischke BV, Molyneaux JM, Moon JB, Owen DR, Rogier DJ, Rumsey JM, Tollefson MB, Walker JK, Bond BR, MacInnes A, Yu Y., Zheng Y

Journal

Bioorg Med Chem Lett

Year

2009

DOI

10.1016/j.bmcl.2009.07.019

PubMed

19631533

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