Novel HCV NS5B polymerase inhibitors derived from 4-(1',1'-dioxo-1',4'-dihydro-1'lambda6-benzo[1',2',4']thiadiazin-3'-yl)-5-hydroxy-2H-pyridazin-3-ones: Part 4. Optimization of DMPK properties.

Citation: Sergeeva MV, Zhou Y, Bartkowski DM, Nolan TG, Norris DA, Okamoto E, Kirkovsky L, Kamran R, Lebrun LA, Tsan M, Patel R, Shah AM, Lardy M, Gobbi A, Li LS, Zhao J, Bertolini T, Stankovic N, Sun Z, Murphy DE, Webber SE, Dragovich PS.: Novel HCV NS5B polymerase inhibitors derived from 4-(1',1'-dioxo-1',4'-dihydro-1'lambda6-benzo[1',2',4']thiadiazin-3'-yl)-5-hydroxy-2H-pyridazin-3-ones: Part 4. Optimization of DMPK properties. Bioorg Med Chem Lett, Volume 18 (11), 2008
Authors: Bartkowski DM, Bertolini T, Dragovich PS., Gobbi A, Kamran R, Kirkovsky L, Lardy M, Lebrun LA, Li LS, Murphy DE, Nolan TG, Norris DA, Okamoto E, Patel R, Sergeeva MV, Shah AM, Stankovic N, Sun Z, Tsan M, Webber SE, Zhao J, Zhou Y
Journal: Bioorg Med Chem Lett
Year: 2008
DOI: 10.1016/j.bmcl.2008.04.005
PubMed: 18442904
Machine-readable: REST API RDF

Publication