Discovery of 5-(2-chloro-4'-(1H-imidazol-1-yl)-[1,1'-biphenyl]-4-yl)-1H-tetrazole as potent and orally efficacious S-nitrosoglutathione reductase (GSNOR) inhibitors for the potential treatment of COPD.

Citation: Muthukaman N, Deshmukh S, Tondlekar S, Tambe M, Pisal D, Sarode N, Mhatre S, Chakraborti S, Shah D, Bhosale VM, Kulkarni A, Mahat MYA, Jadhav SB, Gudi GS, Khairatkar-Joshi N, Gharat LA.: Discovery of 5-(2-chloro-4'-(1H-imidazol-1-yl)-[1,1'-biphenyl]-4-yl)-1H-tetrazole as potent and orally efficacious S-nitrosoglutathione reductase (GSNOR) inhibitors for the potential treatment of COPD. Bioorg Med Chem Lett, Volume 28 (23-24), 2018
Authors: Bhosale VM, Chakraborti S, Deshmukh S, Gharat LA., Gudi GS, Jadhav SB, Khairatkar-Joshi N, Kulkarni A, Mahat MYA, Mhatre S, Muthukaman N, Pisal D, Sarode N, Shah D, Tambe M, Tondlekar S
Journal: Bioorg Med Chem Lett
Year: 2018
DOI: 10.1016/j.bmcl.2018.10.012
PubMed: 30340896
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