Discovery of 4-substituted-8-(2-hydroxy-2-phenyl-cyclohexyl)-2,8-diaza-spiro[4.5]decan-1-one as a novel class of highly selective GlyT1 inhibitors with improved metabolic stability.

Citation: Alberati D, Hainzl D, Jolidon S, Krafft EA, Kurt A, Maier A, Pinard E, Thomas AW, Zimmerli D.: Discovery of 4-substituted-8-(2-hydroxy-2-phenyl-cyclohexyl)-2,8-diaza-spiro[4.5]decan-1-one as a novel class of highly selective GlyT1 inhibitors with improved metabolic stability. Bioorg Med Chem Lett, Volume 16 (16), 2006
Authors: Alberati D, Hainzl D, Jolidon S, Krafft EA, Kurt A, Maier A, Pinard E, Thomas AW, Zimmerli D.
Journal: Bioorg Med Chem Lett
Year: 2006
DOI: 10.1016/j.bmcl.2006.05.058
PubMed: 16757170
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