Citation

Axten JM, Medina JR, Feng Y, Shu A, Romeril SP, Grant SW, Li WH, Heerding DA, Minthorn E, Mencken T, Atkins C, Liu Q, Rabindran S, Kumar R, Hong X, Goetz A, Stanley T, Taylor JD, Sigethy SD, Tomberlin GH, Hassell AM, Kahler KM, Shewchuk LM, Gampe RT.: Discovery of 7-methyl-5-(1-{[3-(trifluoromethyl)phenyl]acetyl}-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (GSK2606414), a potent and selective first-in-class inhibitor of protein kinase R (PKR)-like endoplasmic reticulum kinase (PERK). J Med Chem, Volume 55 (16), 2012

Authors

Atkins C, Axten JM, Feng Y, Gampe RT., Goetz A, Grant SW, Hassell AM, Heerding DA, Hong X, Kahler KM, Kumar R, Li WH, Liu Q, Medina JR, Mencken T, Minthorn E, Rabindran S, Romeril SP, Shewchuk LM, Shu A, Sigethy SD, Stanley T, Taylor JD, Tomberlin GH

Journal

J Med Chem

Year

2012

DOI

10.1021/jm300713s

PubMed

22827572

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