Discovery of canagliflozin, a novel C-glucoside with thiophene ring, as sodium-dependent glucose cotransporter 2 inhibitor for the treatment of type 2 diabetes mellitus.

Citation: Nomura S, Sakamaki S, Hongu M, Kawanishi E, Koga Y, Sakamoto T, Yamamoto Y, Ueta K, Kimata H, Nakayama K, Tsuda-Tsukimoto M.: Discovery of canagliflozin, a novel C-glucoside with thiophene ring, as sodium-dependent glucose cotransporter 2 inhibitor for the treatment of type 2 diabetes mellitus. J Med Chem, Volume 53 (17), 2010
Authors: Hongu M, Kawanishi E, Kimata H, Koga Y, Nakayama K, Nomura S, Sakamaki S, Sakamoto T, Tsuda-Tsukimoto M., Ueta K, Yamamoto Y
Journal: J Med Chem
Year: 2010
DOI: 10.1021/jm100332n
PubMed: 20690635
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