Discovery and biological evaluation of 5-aryl-2-furfuramides, potent and selective blockers of the Nav1.8 sodium channel with efficacy in models of neuropathic and inflammatory pain.

Publication

Citation
Kort ME, Drizin I, Gregg RJ, Scanio MJ, Shi L, Gross MF, Atkinson RN, Johnson MS, Pacofsky GJ, Thomas JB, Carroll WA, Krambis MJ, Liu D, Shieh CC, Zhang X, Hernandez G, Mikusa JP, Zhong C, Joshi S, Honore P, Roeloffs R, Marsh KC, Murray BP, Liu J, Werness S, Faltynek CR, Krafte DS, Jarvis MF, Chapman ML, Marron BE.: Discovery and biological evaluation of 5-aryl-2-furfuramides, potent and selective blockers of the Nav1.8 sodium channel with efficacy in models of neuropathic and inflammatory pain. J Med Chem, Volume 51 (3), 2008
Authors
Atkinson RN, Carroll WA, Chapman ML, Drizin I, Faltynek CR, Gregg RJ, Gross MF, Hernandez G, Honore P, Jarvis MF, Johnson MS, Joshi S, Kort ME, Krafte DS, Krambis MJ, Liu D, Liu J, Marron BE., Marsh KC, Mikusa JP, Murray BP, Pacofsky GJ, Roeloffs R, Scanio MJ, Shi L, Shieh CC, Thomas JB, Werness S, Zhang X, Zhong C
Journal
J Med Chem
Year
2008
PubMed
18176998
Machine-readable
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Palacky University Olomouc

Palacky University Olomouc

Faculty of Science

Department of Physical Chemistry

tř. 17. listopadu 1192/12

771 46 Olomouc

Czech Republic

How to cite?

Juračka J., Šrejber M., Melíková M., Bazgier V., Berka K.: MolMeDB: Molecules on Membranes Database. Database, Volume 2019, 2019, baz078, https://doi.org/10.1093/database/baz078

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