Synthesis and toxicopharmacological evaluation of m-hydroxymexiletine, the first metabolite of mexiletine more potent than the parent compound on voltage-gated sodium channels.

Citation: Catalano A, Desaphy JF, Lentini G, Carocci A, Di Mola A, Bruno C, Carbonara R, De Palma A, Budriesi R, Ghelardini C, Perrone MG, Colabufo NA, Conte Camerino D, Franchini C.: Synthesis and toxicopharmacological evaluation of m-hydroxymexiletine, the first metabolite of mexiletine more potent than the parent compound on voltage-gated sodium channels. J Med Chem, Volume 55 (3), 2012
Authors: Bruno C, Budriesi R, Carbonara R, Carocci A, Catalano A, Colabufo NA, Conte Camerino D, De Palma A, Desaphy JF, Di Mola A, Franchini C., Ghelardini C, Lentini G, Perrone MG
Journal: J Med Chem
Year: 2012
DOI: 10.1021/jm201197z
PubMed: 22191686
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