Tumor Targeting with Novel Pyridyl 6-Substituted Pyrrolo[2,3- d]Pyrimidine Antifolates via Cellular Uptake by Folate Receptor α and the Proton-Coupled Folate Transporter and Inhibition of De Novo Purine Nucleotide Biosynthesis.

Citation: Ravindra M, Wallace-Povirk A, Karim MA, Wilson MR, O'Connor C, White K, Kushner J, Polin L, George C, Hou Z, Matherly LH, Gangjee A.: Tumor Targeting with Novel Pyridyl 6-Substituted Pyrrolo[2,3- d]Pyrimidine Antifolates via Cellular Uptake by Folate Receptor α and the Proton-Coupled Folate Transporter and Inhibition of De Novo Purine Nucleotide Biosynthesis. J Med Chem, Volume 61 (5), 2018
Authors: Gangjee A., George C, Hou Z, Karim MA, Kushner J, Matherly LH, O'Connor C, Polin L, Ravindra M, Wallace-Povirk A, White K, Wilson MR
Journal: J Med Chem
Year: 2018
DOI: 10.1021/acs.jmedchem.7b01708
PubMed: 29425443
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