substance;substance_identifier;membrane;method;charge;temperature;note;x_min;x_min_acc;g_pen;g_pen_acc;g_wat;g_wat_acc;log_k;log_k_acc;log_perm;log_perm_acc;primary_publication;secondary_publication
L-epinephrine;MM00644;DOPC;CCM18;0;25;;;;;;;;;;-3.57735;;;"in-house calculations"
L-epinephrine;MM00644;DOPC;CCM18;0;25;;1.58;;7.15;;1.58;;;;-3.58;;;"in-house calculations"
L-epinephrine;MM00644;CACO;ECACO;+1;37;;;;;;;;;;-6.02;;;"Camenisch G, Alsenz J, Van De Waterbeemd H, Folkers G: Estimation of permeability by passive diffusion through Caco-2 cell monolayers using the drugs’ lipophilicity and molecular weight. Eur. J. Pharm. Sci., 6, 313–319, 1998"
L-epinephrine;MM00644;CACO;QSAR-PSA;;25;;;;;;;;;;-4.659;;;"Subramanian G, Kitchen DB.: Computational approaches for modeling human intestinal absorption and permeability. J Mol Model, Volume 12 (5), 577-589, 2006"
L-epinephrine;MM00644;CACO;QSAR-HB;;25;;;;;;;;;;-4.176;;;"Subramanian G, Kitchen DB.: Computational approaches for modeling human intestinal absorption and permeability. J Mol Model, Volume 12 (5), 577-589, 2006"
L-epinephrine;MM00644;1-octanol;XLOGP3;;;;;;;;;;-1.4;;;;;"Kim S, Chen J, Cheng T, Gindulyte A, He J, He S, Li Q, Shoemaker BA, Thiessen PA, Yu B, Zaslavsky L, Zhang J, Bolton EE.: PubChem 2023 update. Nucleic Acids Res, Volume 51 (d1), D1373-D1380, 2023"
L-epinephrine;MM00644;EggPC;ELIP;;25;;;;;;;;;;-5.57;;;"Lomize AL, Pogozheva ID: Prediction of passive membrane permeability and translocation pathways of biologically active molecules. Biophys. J., 112(3) Supp1, 525a., 2017."
L-epinephrine;MM00644;LEC;CPMM;0;25;"<a href=https://permm.phar.umich.edu/  target=_blank>PerMM web server</a>";;;;;;;;;-5.48;;;"Lomize AL,Hage JM, Schnitzer K, Golobokov K, LaFaive MB, Forsyth AC, Pogozheva ID: PerMM: A Web Tool and Database for Analysis of Passive Membrane Permeability and Translocation Pathways of Bioactive Molecules. J. Chem. Inf. Model. 59(7), 3094-3099, 2019"
L-epinephrine;MM00644;LEC;CPMM;+1;25;"pH=7.4 ,<a href=https://permm.phar.umich.edu/  target=_blank>PerMM web server</a>";;;;;;;;;-8.13;;;"Lomize AL,Hage JM, Schnitzer K, Golobokov K, LaFaive MB, Forsyth AC, Pogozheva ID: PerMM: A Web Tool and Database for Analysis of Passive Membrane Permeability and Translocation Pathways of Bioactive Molecules. J. Chem. Inf. Model. 59(7), 3094-3099, 2019"
L-epinephrine;MM00644;CACO;ECACO;0;25;"<a href=https://pubchem.ncbi.nlm.nih.gov/bioassay/455986  target=_blank>455986</a>";;;;;;;;;-6.02;;;"Kim S, Chen J, Cheng T, Gindulyte A, He J, He S, Li Q, Shoemaker BA, Thiessen PA, Yu B, Zaslavsky L, Zhang J, Bolton EE.: PubChem 2023 update. Nucleic Acids Res, Volume 51 (d1), D1373-D1380, 2023"
L-epinephrine;MM00644;CACO;ECACO;0;25;"<a href=https://pubchem.ncbi.nlm.nih.gov/bioassay/592681  target=_blank>592681</a>";;;;;;;;;-6.02;;;"Kim S, Chen J, Cheng T, Gindulyte A, He J, He S, Li Q, Shoemaker BA, Thiessen PA, Yu B, Zaslavsky L, Zhang J, Bolton EE.: PubChem 2023 update. Nucleic Acids Res, Volume 51 (d1), D1373-D1380, 2023"
L-epinephrine;MM00644;CACO;ECACO;0;25;"<a href=https://pubchem.ncbi.nlm.nih.gov/bioassay/1223490  target=_blank>1223490</a>";;;;;;;;;-6.02;;;"Kim S, Chen J, Cheng T, Gindulyte A, He J, He S, Li Q, Shoemaker BA, Thiessen PA, Yu B, Zaslavsky L, Zhang J, Bolton EE.: PubChem 2023 update. Nucleic Acids Res, Volume 51 (d1), D1373-D1380, 2023"