substance;substance_identifier;target;type;note;Km;Km_acc;EC50;EC50_acc;Ki;Ki_acc;IC50;IC50_acc;primary_publication;secondary_publication
Rolofylline;MM17336;SLC22A11;Non-inhibitor;;;;;;4.68;;;;"Enomoto A, Takeda M, Shimoda M, Narikawa S, Kobayashi Y, Kobayashi Y, Yamamoto T, Sekine T, Cha SH, Niwa T, Endou H.: Interaction of human organic anion transporters 2 and 4 with organic anion transport inhibitors. J Pharmacol Exp Ther, Volume 301 (3), 2002";"Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR.: The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res, Volume 52 (d1), D1180-D1192, 2024"
Rolofylline;MM17336;SLC22A6;Inhibitor;;;;;;5.11;;;;"Takeda M, Narikawa S, Hosoyamada M, Cha SH, Sekine T, Endou H.: Characterization of organic anion transport inhibitors using cells stably expressing human organic anion transporters. Eur J Pharmacol, Volume 419 (2-3), 2001";"Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR.: The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res, Volume 52 (d1), D1180-D1192, 2024"
Rolofylline;MM17336;SLC22A8;Inhibitor;;;;;;5.43;;;;"Takeda M, Narikawa S, Hosoyamada M, Cha SH, Sekine T, Endou H.: Characterization of organic anion transport inhibitors using cells stably expressing human organic anion transporters. Eur J Pharmacol, Volume 419 (2-3), 2001";"Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR.: The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res, Volume 52 (d1), D1180-D1192, 2024"