Datasets
Authors | Title | Journal | Year | PMID/DOI | Actions | ||||||
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10.1007/s00044-012-0180-1 |
10.1007/s00044-... |
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Raj N. Misra, Yolanda F. Kelly, Bärbel R. Brown, Daniel...
Raj N. Misra, Yolanda F. Kelly, Bärbel R. Brown, Daniel G.M. Roberts, Saeho Chong, Steven M. Seiler
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Argatroban analogs: Synthesis, thrombin inhibitory activity and cell permeability of aminoheterocyclic guanidine... |
Bioorganic & Medicinal Chemistry Letters | 1994 | 10.1016/S0960-8... |
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T.K. Sawyer, J.F. Fisher, J.B. Hester, C.W. Smith, A.G....
T.K. Sawyer, J.F. Fisher, J.B. Hester, C.W. Smith, A.G. Tomasselli, W.G. Tarpley, P.S. Burton, J.O. Hui, T.J. McQuade, R.A. Conradi, V.S. Bradford, L. Liu, J.H. Kinner, J. Tustin, D.L. Alexander, A.W. Harrison, D.E. Emmert, D.J. Staples, L.L. Maggiora, Y.Z. Zhang, R.A. Poorman, B.M. Dunna, C. Rao, P.E. Scarborough, W.T. Lowther, C. Craik, D. DeCamp, J. Moon, W.J. Howe, R.L. Heinrikson
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Peptidomimetic inhibitors of human immunodeficiency virus protease (HIV-PR): Design, enzyme binding and selectivity,... |
Bioorganic & Medicinal Chemistry Letters | 1993 | 10.1016/S0960-8... |
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Mark G. Saulnier, David B. Frennesson, Milind S. Deshpande,...
Mark G. Saulnier, David B. Frennesson, Milind S. Deshpande, Steven B. Hansel, Dolatrai M. Vyas
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An efficient method for the synthesis of guanidino prodrugs |
Bioorganic & Medicinal Chemistry Letters | 1994 | 10.1016/S0960-8... |
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10.1039/C1MD00093D |
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10.1039/C2MD00271J |
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10.1039/C2MD20190A |
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10.1039/C3MD20368A |
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10.1039/C5MD00043B |
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A M Subbaiah M, Mandlekar S, Desikan S, Ramar T, Subramani...
A M Subbaiah M, Mandlekar S, Desikan S, Ramar T, Subramani L, Annadurai M, Desai SD, Sinha S, Jenkins SM, Krystal MR, Subramanian M, Sridhar S, Padmanabhan S, Bhutani P, Arla R, Singh S, Sinha J, Thakur M, Kadow JF, Meanwell NA.
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Design, Synthesis, and Pharmacokinetic Evaluation of Phosphate and Amino Acid Ester Prodrugs for Improving the Oral... |
J Med Chem | 2019 | 30938524 |
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Abás S, Rodríguez-Arévalo S, Bagán A, Griñán-Ferré...
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Bicyclic α-Iminophosphonates as High Affinity Imidazoline I2 Receptor Ligands for Alzheimer's Disease. |
J Med Chem | 2020 | 32150414 |
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Abdel-Maksoud MS, El-Gamal MI, Lee BS, Gamal El-Din MM,...
Abdel-Maksoud MS, El-Gamal MI, Lee BS, Gamal El-Din MM, Jeon HR, Kwon D, Ammar UM, Mersal KI, Ali EMH, Lee KT, Yoo KH, Han DK, Lee JK, Kim G, Choi HS, Kwon YJ, Lee KH, Oh CH.
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Discovery of New Imidazo[2,1-b]thiazole Derivatives as Potent Pan-RAF Inhibitors with Promising In Vitro... |
J Med Chem | 2021 | 33999621 |
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Abdul-Hay S, Schiefer IT, Chandrasena RE, Li M, Abdelhamid...
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NO-SSRIs: Nitric Oxide Chimera Drugs Incorporating a Selective Serotonin Reuptake Inhibitor. |
ACS Med Chem Lett | 2011 |
21927645 DOI: 10.1021/ml2000033
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Abe T, Kakyo M, Tokui T, Nakagomi R, Nishio T, Nakai D,...
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Identification of a novel gene family encoding human liver-specific organic anion transporter LST-1. |
J Biol Chem | 1999 | 10358072 |
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Abe T, Unno M, Onogawa T, Tokui T, Kondo TN, Nakagomi R,...
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LST-2, a human liver-specific organic anion transporter, determines methotrexate sensitivity in gastrointestinal... |
Gastroenterology | 2001 | 11375950 |
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Abla N, Bashyam S, Charman SA, Greco B, Hewitt P,...
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Long-Lasting and Fast-Acting in Vivo Efficacious Antiplasmodial Azepanylcarbazole Amino Alcohol. |
ACS Med Chem Lett | 2017 | 29259752 |
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Ablordeppey SY, Altundas R, Bricker B, Zhu XY, Kumar EV,...
Ablordeppey SY, Altundas R, Bricker B, Zhu XY, Kumar EV, Jackson T, Khan A, Roth BL.
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Identification of a butyrophenone analog as a potential atypical antipsychotic agent:... |
Bioorg Med Chem | 2008 | 18595716 |
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K. Abrahamsson, P. Andersson, J. Bergman, U. Bredberg, ...
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Discovery of AZD8165 – a clinical candidate from a novel series of neutral thrombin inhibitors |
MedChemComm | 2016 |
10.1039/C5MD004... DOI: 10.1039/C5MD00479A
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Abram M, Jakubiec M, Reeb K, Cheng MH, Gedschold R, Rapacz...
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Discovery of (R)-N-Benzyl-2-(2,5-dioxopyrrolidin-1-yl)propanamide [(R)-AS-1], a Novel... |
J Med Chem | 2022 | 35984707 |
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Achermann G, Ballard TM, Blasco F, Broutin PE, Büttelmann...
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Discovery of the imidazo[1,5-a][1,2,4]-triazolo[1,5-d][1,4]benzodiazepine scaffold as a novel, potent and selective... |
Bioorg Med Chem Lett | 2009 | 19726184 |
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Acker BA, Jacobsen EJ, Rogers BN, Wishka DG, Reitz SC,...
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Discovery of N-[(3R,5R)-1-azabicyclo[3.2.1]oct-3-yl]furo[2,3-c]pyridine-5-carboxamide as an agonist of the alpha7... |
Bioorg Med Chem Lett | 2008 | 18490160 |
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Acker TM, Khatri A, Vance KM, Slabber C, Bacsa J, Snyder...
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Structure-activity relationships and pharmacophore model of a noncompetitive pyrazoline containing class of... |
J Med Chem | 2013 |
23909910 DOI: 10.1021/jm400652r
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Adachi H, Suzuki T, Abe M, Asano N, Mizutamari H, Tanemoto...
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Molecular characterization of human and rat organic anion transporter OATP-D. |
Am J Physiol Renal Physiol | 2003 | 14631946 |
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Adachi Y, Suzuki H, Sugiyama Y.
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Comparative studies on in vitro methods for evaluating in vivo function of MDR1 P-glycoprotein. |
Pharm Res | 2001 | 11785684 |
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Adam JM, Clark JK, Davies K, Everett K, Fields R, Francis...
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Low brain penetrant CB1 receptor agonists for the treatment of neuropathic pain. |
Bioorg Med Chem Lett | 2012 | 22421020 |
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Discovery of GSK1070916, a potent and selective inhibitor of Aurora B/C kinase. |
J Med Chem | 2010 |
20420387 DOI: 10.1021/jm901870q
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Development of Robust 17(R),18(S)-Epoxyeicosatetraenoic Acid (17,18-EEQ) Analogues as Potential Clinical... |
J Med Chem | 2019 | 31693857 |
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Adelstein GW, Yen CH, Haack RA, Yu S, Gullikson G, Price...
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Substituted 2-[(2-benzimidazolylsulfinyl)methyl]anilines as potential inhibitors of H+/K+ ATPase. |
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Semicarbazone-based inhibitors of cathepsin K, are they prodrugs for aldehyde inhibitors? |
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Design and synthesis of novel P2 substituents in diol-based HIV protease inhibitors. |
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Novel N-substituted 3 alpha-[bis(4'-fluorophenyl)methoxy]tropane analogues: selective ligands for the dopamine... |
J Med Chem | 1997 |
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Genotype-dependent effects of inhibitors of the organic cation transporter, OCT1: predictions of metformin interactions. |
Pharmacogenomics J | 2011 |
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Arylcyclopropanecarboxyl guanidines as novel, potent, and selective inhibitors of the sodium hydrogen exchanger... |
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1,2,4-Triazolo-[1,5-a]pyridine HIF Prolylhydroxylase Domain-1 (PHD-1) Inhibitors With a Novel Monodentate Binding... |
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Synthesis and Biological Evaluation of Novel Olean-28,13β-lactams as Potential Antiprostate Cancer Agents. |
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Design and synthesis of a novel series of cyclohexyloxy-pyridyl derivatives as inhibitors of diacylglycerol acyl... |
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Identification and optimization of anthranilic sulfonamides as novel, selective cholecystokinin-2 receptor antagonists. |
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