{"data":{"id":956,"citation":"Zhu Y, de Jesus RK, Tang H, Walsh SP, Jiang J, Gu X, Teumelsan N, Shahripour A, Pio B, Ding FX, Ha S, Priest BT, Swensen AM, Alonso-Galicia M, Felix JP, Brochu RM, Bailey T, Thomas-Fowlkes B, Zhou X, Pai LY, Hampton C, Hernandez M, Owens K, Ehrhart J, Roy S, Kaczorowski GJ, Yang L, Parmee ER, Sullivan K, Garcia ML, Pasternak A.: Discovery of a potent and selective ROMK inhibitor with improved pharmacokinetic properties based on an octahydropyrazino[2,1-c][1,4]oxazine scaffold. Bioorg Med Chem Lett, Volume 26 (23), 2016","title":"Discovery of a potent and selective ROMK inhibitor with improved pharmacokinetic properties based on an octahydropyrazino[2,1-c][1,4]oxazine scaffold.","doi":"10.1016\/j.bmcl.2016.10.064","doi_url":"https:\/\/doi.org\/10.1016\/j.bmcl.2016.10.064","pmid":"27839686","pmid_url":"https:\/\/pubmed.ncbi.nlm.nih.gov\/27839686\/","year":2016,"journal":"Bioorg Med Chem Lett","volume":"26","issue":"23","page":"5695-5702","authors":[{"first_name":"Alonso-Galicia M","last_name":null,"full_name":null},{"first_name":"Bailey T","last_name":null,"full_name":null},{"first_name":"Brochu RM","last_name":null,"full_name":null},{"first_name":"de Jesus RK","last_name":null,"full_name":null},{"first_name":"Ding FX","last_name":null,"full_name":null},{"first_name":"Ehrhart J","last_name":null,"full_name":null},{"first_name":"Felix JP","last_name":null,"full_name":null},{"first_name":"Garcia ML","last_name":null,"full_name":null},{"first_name":"Gu X","last_name":null,"full_name":null},{"first_name":"Ha S","last_name":null,"full_name":null},{"first_name":"Hampton C","last_name":null,"full_name":null},{"first_name":"Hernandez M","last_name":null,"full_name":null},{"first_name":"Jiang J","last_name":null,"full_name":null},{"first_name":"Kaczorowski GJ","last_name":null,"full_name":null},{"first_name":"Owens K","last_name":null,"full_name":null},{"first_name":"Pai LY","last_name":null,"full_name":null},{"first_name":"Parmee ER","last_name":null,"full_name":null},{"first_name":"Pasternak A.","last_name":null,"full_name":null},{"first_name":"Pio B","last_name":null,"full_name":null},{"first_name":"Priest BT","last_name":null,"full_name":null},{"first_name":"Roy S","last_name":null,"full_name":null},{"first_name":"Shahripour A","last_name":null,"full_name":null},{"first_name":"Sullivan K","last_name":null,"full_name":null},{"first_name":"Swensen AM","last_name":null,"full_name":null},{"first_name":"Tang H","last_name":null,"full_name":null},{"first_name":"Teumelsan N","last_name":null,"full_name":null},{"first_name":"Thomas-Fowlkes B","last_name":null,"full_name":null},{"first_name":"Walsh SP","last_name":null,"full_name":null},{"first_name":"Yang L","last_name":null,"full_name":null},{"first_name":"Zhou X","last_name":null,"full_name":null},{"first_name":"Zhu Y","last_name":null,"full_name":null}],"url":"https:\/\/molmedb.upol.cz\/api\/v1\/publications\/956","landing_page":"https:\/\/molmedb.upol.cz\/publication\/956","created_at":"2020-08-24T13:57:32.000000Z","updated_at":null}}