{"data":{"id":5025,"citation":"Svobodova B, Moravcova Z, Misiachna A, Novakova G, Marek A, Finger V, Odvarkova J, Pejchal J, Karasova JZ, Netolicky J, Ladislav M, Hrabinova M, Sorf A, Muckova L, Fikejzlova L, Benkova M, Novak M, Prchal L, Capek J, Handl J, Rousar T, Greber KE, Ciura K, Horak M, Soukup O, Korabecny J.: Novel tacrine-based multi-target directed Ligands: Enhancing cholinesterase inhibition, NMDA receptor antagonism, and CNS bioavailability for Alzheimer's disease treatment.. European journal of medicinal chemistry, Volume 292, 117678, 2025","title":"Novel tacrine-based multi-target directed Ligands: Enhancing cholinesterase inhibition, NMDA receptor antagonism, and CNS bioavailability for Alzheimer's disease treatment.","doi":"10.1016\/j.ejmech.2025.117678","doi_url":"https:\/\/doi.org\/10.1016\/j.ejmech.2025.117678","pmid":"40288120","pmid_url":"https:\/\/pubmed.ncbi.nlm.nih.gov\/40288120\/","year":2025,"journal":"European journal of medicinal chemistry","volume":"292","issue":null,"page":"117678","authors":[{"first_name":"Barbora","last_name":"Svobodova","full_name":"Svobodova B"},{"first_name":"Zuzana","last_name":"Moravcova","full_name":"Moravcova Z"},{"first_name":"Anna","last_name":"Misiachna","full_name":"Misiachna A"},{"first_name":"Gabriela","last_name":"Novakova","full_name":"Novakova G"},{"first_name":"Ales","last_name":"Marek","full_name":"Marek A"},{"first_name":"Vladimir","last_name":"Finger","full_name":"Finger V"},{"first_name":"Jitka","last_name":"Odvarkova","full_name":"Odvarkova J"},{"first_name":"Jaroslav","last_name":"Pejchal","full_name":"Pejchal J"},{"first_name":"Jana Zdarova","last_name":"Karasova","full_name":"Karasova JZ"},{"first_name":"Jakub","last_name":"Netolicky","full_name":"Netolicky J"},{"first_name":"Marek","last_name":"Ladislav","full_name":"Ladislav M"},{"first_name":"Martina","last_name":"Hrabinova","full_name":"Hrabinova M"},{"first_name":"Ales","last_name":"Sorf","full_name":"Sorf A"},{"first_name":"Lubica","last_name":"Muckova","full_name":"Muckova L"},{"first_name":"Lenka","last_name":"Fikejzlova","full_name":"Fikejzlova L"},{"first_name":"Marketa","last_name":"Benkova","full_name":"Benkova M"},{"first_name":"Martin","last_name":"Novak","full_name":"Novak M"},{"first_name":"Lukas","last_name":"Prchal","full_name":"Prchal L"},{"first_name":"Jan","last_name":"Capek","full_name":"Capek J"},{"first_name":"Jiri","last_name":"Handl","full_name":"Handl J"},{"first_name":"Tomas","last_name":"Rousar","full_name":"Rousar T"},{"first_name":"Katarzyna Ewa","last_name":"Greber","full_name":"Greber KE"},{"first_name":"Krzesimir","last_name":"Ciura","full_name":"Ciura K"},{"first_name":"Martin","last_name":"Horak","full_name":"Horak M"},{"first_name":"Ondrej","last_name":"Soukup","full_name":"Soukup O"},{"first_name":"Jan","last_name":"Korabecny","full_name":"Korabecny J"}],"url":"https:\/\/molmedb.upol.cz\/api\/v1\/publications\/5025","landing_page":"https:\/\/molmedb.upol.cz\/publication\/5025","created_at":"2026-07-13T13:09:55.000000Z","updated_at":"2026-07-13T13:09:55.000000Z"}}