{"data":{"id":4845,"citation":"Cheng H., Hoffman J., Le P., Pairish M., Kania R., Farrell W., Bagrodia S., Yuan J., Sun S., Zhang E., Xiang C., Dalvie D., Rahavendran S.: Structure-based design, SAR analysis and antitumor activity of PI3K\/mTOR dual inhibitors from 4-methylpyridopyrimidinone series. Bioorganic & Medicinal Chemistry Letters, Volume 23 (9), 2013","title":"Structure-based design, SAR analysis and antitumor activity of PI3K\/mTOR dual inhibitors from 4-methylpyridopyrimidinone series","doi":"10.1016\/j.bmcl.2013.02.020","doi_url":"https:\/\/doi.org\/10.1016\/j.bmcl.2013.02.020","pmid":null,"year":2013,"journal":"Bioorganic & Medicinal Chemistry Letters","volume":"23","issue":"9","page":null,"authors":[{"first_name":"Hengmiao","last_name":"Cheng","full_name":"Hengmiao Cheng"},{"first_name":"Jacqui E.","last_name":"Hoffman","full_name":"Jacqui E. Hoffman"},{"first_name":"Phuong T.","last_name":"Le","full_name":"Phuong T. Le"},{"first_name":"Mason","last_name":"Pairish","full_name":"Mason Pairish"},{"first_name":"Robert","last_name":"Kania","full_name":"Robert Kania"},{"first_name":"William","last_name":"Farrell","full_name":"William Farrell"},{"first_name":"Shubha","last_name":"Bagrodia","full_name":"Shubha Bagrodia"},{"first_name":"Jing","last_name":"Yuan","full_name":"Jing Yuan"},{"first_name":"Shaoxian","last_name":"Sun","full_name":"Shaoxian Sun"},{"first_name":"Eric","last_name":"Zhang","full_name":"Eric Zhang"},{"first_name":"Cathy","last_name":"Xiang","full_name":"Cathy Xiang"},{"first_name":"Deepak","last_name":"Dalvie","full_name":"Deepak Dalvie"},{"first_name":"Sadayappan V.","last_name":"Rahavendran","full_name":"Sadayappan V. Rahavendran"}],"url":"https:\/\/molmedb.upol.cz\/api\/v1\/publications\/4845","landing_page":"https:\/\/molmedb.upol.cz\/publication\/4845","created_at":"2026-06-22T14:36:34.000000Z","updated_at":"2026-06-22T14:36:34.000000Z"}}